Protein Characterization Services

Affinity Characterization Service. For services that require the detection and monitoring of biomolecular interactions in real time, Kemp Proteins uses the ForteBio OctetRed96e system.. Kemp Proteins experienced team of protein / antibody characterization scientists utilize modern characterization instrumentation and affinity protocols to.
Protein characterization services. Protein Characterization & Testing Haemtech Biopharma can run a myriad of analytical techniques to provide a biochemical analysis of your proteinaceous drug product or substance or to assist with contaminant identification. Services Protein Characterization. Analytical characterization ensures the identity, purity, structural and conformational integrity, and function of the protein. We perform a number of routine protein analyses throughout all project stages. If needed, we can submit your samples for additional methods of characterization. Protein Characterization Services With a wide array of GMP protein characterization services supporting recombinant glycoproteins and complex biologics, our experience in building quality infrastructures and scientific experts can help overcome any challenges to accomplish your project objectives from Pre-IND to BLA. Analytical Protein Characterization ensures the identity, purity, structural and conformational integrity and activity of a protein. The precise amino acid sequence, molecular weight, charge variances, glycosylation, aggregation level, and oxidation level are all key components of thorough characterization of recombinant protein.
Protein Concentration Analysis; Find out more about our comprehensive range of protein characterization services along with our state of the art technology, dedicated customer service, and expert technical support. Get in touch with us today to discover how we can help support your drug’s development. Protein characterization services. Custom molecular biology and biochemistry services. Advansta supports life science researchers with custom protein analysis services. Our expert team can help with experimental design and implementation at any point in your project. Inquire Now. Protein Service (PS) offers recombinant protein expression, protein purification and biophysical characterization for drug discovery and life science research. The proteins may be used in structural biology, protein-ligand and protein-protein interaction studies, and in development of diagnostics. Protein Characterization Detailed analysis of protein structure is of vital importance in the study of protein functions and the development of biologics. Our Protein Characterization services offer in-depth analysis of the primary structure and disulfide bond linkage of purified or expressed proteins.
Protein Characterization. The Nexelis protein characterization platform provides a comprehensive range of high-quality analytical assays to ensure the identity, purity and physicochemical properties of the protein of interest. We perform several routine protein analyses throughout the project to ensure quality control and minimal batch-to-batch. Overview of Protein Purity and Homogeneity Characterization Service At Creative Proteomics, we provide a complete list of protein purity and homogeneity characterization services to detect contaminants, protein variants, isomers, mismatched S-S link, truncated proteins, degraded proteins, protein modifications, protein aggregates, and protein. For characterization of oligomeric state and aggregation, APL offers analytical ultracentrifugation (AUC), light scattering, and native gel electrophoresis analysis services. For characterization of protein conformation and stability we, primarily use circular dichroism (CD), differential scanning calorimetry (DSC), and fluorescence, but native. Protein Characterization. We provide a comprehensive range of high-quality analytical assays to characterize protein therapeutics. Whether characterizing the original or subsequent reference standards, evaluating production lots to those standards or performing comparability studies of biosimilars or biobetters, we have the full-range of.
Protein characterization is a critical part of CMC development for any therapeutic protein (i.e., a Biologic). Modern biotechnology has enabled the development of well-characterized biologics, which includes monoclonal antibodies and recombinant proteins. Therefore, the analysis is an important part of the protein characterization needed for biologics. Sequence coverage of proteins can be optimized by careful selection of proteases for the digest. Our peptide mapping services can also provide detailed information about post-translational modifications – including deamidation and oxidation. Alphalyse protein services are optimized for a wide range of protein-based biologics. With experience from thousands of analytical runs and more than 100 HCP analysis projects, we are a an experienced protein characterization CRO, with an established and validated workflow for most expression systems and sample types. A thorough characterization of the studied protein can be achieved by the quantitative determination of the protein concentration, for example by using amino acid analysis. Or, the measuring of the absorbance of the protein in solution at 280 nm using an ultraviolet (UV) spectrophotometer.
Protein characterization Solvias provides comprehensive cGMP services at every stage of drug development. We can fully characterize any protein biopharmaceuticals for the Chemistry and Manufacturing Controls (CMC) section of Investigational New Drug applications (INDs), New Drug Applications (NDAs) and Biologic License Applications (BLAs). Protein Sciences. Syngene's comprehensive gene-to-protein services start with cloning the gene and extend up to the supply of ready-to-use proteins. Proteins can be supplied as per the specific needs of the client - ranging from mg to gram scale and varying from research grade to highly pure crystallography grade. GenScript's experts have expertise to take both recombinant proteins and monoclonal antibodies, from research and product development through characterization and quality control tests. Services are available for both standalone analytical assays and broad testing programs, to meet your specific needs. SERVICES. Protagen Protein Services (PPS) is a world leading CRO and recognized expert for analytical services in protein science regarding characterization, method development, validation and routine testing of antibodies, proteins, vaccines and other formates of biopharmaceuticals.
BioPharmaSpec provides a comprehensive range of protein characterization services to meet global regulatory requirements for biopharmaceutical characterization.. The harmonised ICH guideline Q6b suggests that characterization of a biopharmaceutical should include:. Structural characterization. Glycosylation and Glycan characterization. N-linked glycosylation