Single Use Bioreactor

Figure 1: Features of the Thermo Fisher HyPerforma 2,000-L single-use bioreactor As the biopharmaceutical industry continues toward streamlined bioprocessing and intensified cell-culture biology, selection criteria of single-use bioreactors (S.U.B.s) and other bioprocessing technologies will become increasingly rigorous, emphasizing the.

Single use bioreactor. Single-use bioreactor helps in mitigating the risk of cross-contamination, especially during the production of multi-drugs at pharmaceutical manufacturing units. This is helping the pharmaceutical companies save time and also leads to the significant cost saving. Due to these factors, there has been a high preference for single-use bioreactors. Scalable, Simple, Smart and Reliable. Mobius® Single-Use Bioreactors are a scalable portfolio of stirred tank bioreactors that provide flexibility by configuring software, hardware, and single-use assemblies for use in fed-batch and perfusion applications.. The Mobius® Bioreactor family includes the bench scale (3 L), pilot-scale (50 L and 200 L) , and clinical scale (1000 L and 2000 L. The UniVessel® SU is a stirred tank single-use bioreactor with a working volume range from 0.6 - 2 L. It is entirely single use from vessel to sensor and can easily be connected to your existing bioreactor. It combines the proven, scalable design of glass bioreactors and the fast turnaround of single-use systems. The global single-use bioreactor market is expected to witness a CAGR of 15.5% during the forecast period. Certain factors that are driving the market's growth include rapid adoption of single-use technologies (SUTs) by the industry, cost-effectiveness and lower downtime, and launch of new products.

BioBLU vessels are designed for use with the Eppendorf DASbox® and DASGIP® Parallel Bioreactor Systems, BioFlo® 120, and BioFlo 320. A range of adaptor kits is offered as well, enabling your existing bioreactor system for single-use operation without the expense of replacing the whole system. BioBLU Single-Use Vessel Bundles provide you with. Choosing The Right Single Use Bioreactor. Single Use Bioreactors (SUBs) are now being widely adopted because they eliminate the need for cleaning, which reduces downtime and makes the cGMP process easier. Advantages of single use >> Why Use Tangential Flow Filtration? A single-use bioreactor or disposable bioreactor is a bioreactor with a disposable bag instead of a culture vessel. Typically, this refers to a bioreactor in which the lining in contact with the cell culture will be plastic, and this lining is encased within a more permanent structure (typically, either a rocker or a cuboid or cylindrical steel support). The Thermo Scientific HyPerforma Single-Use Bioreactor (S.U.B.) is widely adopted in process development (PD), clinical trials, and cGMP cell culture production. The design and features of the HyPerforma S.U.B. have been steadily improved since its launch in 2006 to meet the increasing performance demands required by current cell culture processes.

The SB10-X is an orbital shaken benchtop bioreactor system for the cultivation of human, mammalian and plant cells in a single-use bag. It consists of six modules (excluding the bag) and has a working volume from 4 litres up to 12 litres. The SB10-X can be used in research, process development or as a pilot scale bioreactor. Single-use bioreactor consumables are commonly purchased when needed, but a stock is required as a back-up. The size of the stock is dependent on, for example, the business need and the delivery time of the consumable. However, bulky mixing devices will require large storage space and add to the complexity of the logistics. In addition, very. The single-use bioreactor systems segment dominated the single-use bioreactors market in 2019. SUB systems offer benefits such as lower capital investment, lower operating expenses, and lower environmental footprint, thus driving the growing adoption of these systems in biopharma applications. The ergonomics of installing single-use bioreactors and ancillary single-use systems into support hardware is an important concern for many users, which can be addressed through careful bioreactor design. Pall offers a complete range of scalable, single-use bioreactors for process development and cGMP manufacturing.

The Allegro STR bioreactor family combines Pall’s bioprocess engineering expertise, cell culture know-how and our drive for quality into a series of single-use bioreactors that deliver consistent and scalable cell culture performance across the range. The bioreactor market’s first disposable and scalable solution. The single-use bioreactor market generated $202.5 million last year, according to Markets and Markets. 1 Its market research points to an 18.4 percent increase, reaching $470.9 million by 2019. Single-use technologies primarily include disposable bioreactors, mixers, containers, tubing, connectors, sampling systems, purification. Today Sartorius offers a wide variety of single-use bioreactors which are ideal for mammalian cell culture, very demanding high cell-density or microcarrier-based processes. Our single-use bioreactors from 15 mL working volume with Ambr® 15 to Biostat® STR 2,000 L have been developed to ensure easy and straightforward scale-up and scale-down. Single-use vessels eliminate autoclaving, improve turn-around time, simplify validation, and reduce overall costs. The BioBLU portfolio has grown to accommodate users from early research and development through manufacturing. BioBLU c and p vessels cover a wide variety of processes, including shear-sensitive suspension cell cultures and.

In addition to the most advanced single-use bioreactors, we now provide world-class process development and scale-up services Vertical-Wheel ™ Bioreactor Product Family Our line of innovative single-use bioreactors can provide homogeneous, low-shear, and scalable mixing across a wide range of working volumes Single use bioreactor. The EDF-5.4 monoblock can be adapted for single use bioreactor control. For example, we have expierence in application of single use vessels from CerCell (Danmark). CerCell has configurable vessels of different volumes (0.5 to75 liters). These vessels are equipped with all necessary accessories to provide fermentations of. An increasing number of commercial mAb plants is utilizing single use equipment, mainly because of the high flexibility.In most cases, the reactor size is 2000 l (the so-called 2K bioreactor), which is a standard in the industry.Up to now, 2K is the largest volume with proven track records for single use bioreactors. Single-use Bioreactor Systems. Speed and flexibility in cell culture operations from process development to large-scale biomanufacturing. Increased facility utilization. Single-use equipment reduces the need for costly and time-consuming cleaning and validation procedures between batches.

The Thermo Scientific HyPerforma Single-Use Bioreactor (S.U.B.) is widely adopted in process development (PD), clinical trials, and cGMP cell culture production. The design and features of the HyPerforma S.U.B. have been steadily improved since its launch in 2006 to meet the increasing performance demands required by current cell culture processes.